Sanesco products may not be sold online. For information on how to order, please call 949-600-5100.
SomniTR™ is a delayed-released formula, designed to release 1mg of melatonin initially and 1mg three hours later, to help promote the ability to stay asleep. SomniTR™ supports melatonin production and levels through multiple steps in the Serotonin-to-melatonin pathway, and also influences inhibitory GABAergic activity.
Coleus forskohlii: A source of forskolin that increases cAMP, which promotes melatonin synthesis by contributing to the activity of Serotonin N-acetyltransferase, the enzyme that metabolizes Serotonin into the intermediate N-acetylserotonin.Lactium®: Excellent GABA-A receptor agonist; small, hypoallergenic peptide derived from dairy.
Pantethine: Immediate precursor to acetyl coenzyme A, acetyl donor in the production of N-acetylserotonin, the precursor to melatonin.
Melatonin: Neurohormone involved with circadian rhythm regulation and sleep induction.
also influences inhibitory GABAergic activity.
Melatonin deficiency is involved in prolonged sleep latency and the inability to stay asleep, circadian rhythm disorders, and jet lag. Melatonin has also been shown to reduce ACTH-stimulated cortisol production that may interfere with sleep. Disordered circadian rhythm is being studied as another cause for increased appetite stimulation and weight gain. The melatonin in SomniTR™ is delayed-released to provide sustained levels for up to eight hours. Besides melatonin, SomniTR™ combines support for GABA-A receptor sites. GABA-A agonists have shown to improve quality of sleep. Other ingredients are added to the formula to support melatonin synthesis.SomniTR™ provides support for patients with sleep problems in conjunction with Lentra™ and/or Tranquilent™. It helps in supporting melatonin production and may help improve decreased GABA binding.
Contraindicated with history of major depressive disorder.
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