This product has been formulated specifically for support of healthy estrogen metabolism. Both Indol-3-carbanol (I3C) and Diindolylmethionine (DIM) are compounds that naturally occur in cruciferous vegetables, such as broccoli, cauliflower and cabbage. Clinical trials using these compounds show an improvement in estrogen metabolites towards more health ratios. Unhealthy estrogen ratios have been associated with an increased risk for breast cancer. These compounds may be especially beneficial for women with estrogen related health issues. Usual dose is 1-3 capsules daily, or as recommended by your physician.