January 29th, 2012
A soon-to-be-released book, Complementary and Alternative Medicine Treatments in Psychiatry, by Stradford, Vickar, Berger, and Cass, lists a number of nutrient therapies found to be beneficial for mental health problems.
- Niacinamide- for Alzheimer’s disease treatment and prevention- up to 6000 mg daily.
- Methylation supporters- affect dopamine, norepinephrine, and serotonin to impact memory, mood, concentration, and sleep. These include folic acid or tetrahydrofolate, B6, B12, and SAM-e. Folic acid may be low in depression or schizophrenia. Vitamin B12 may improve depression and prevent Alzheimer’s disease. Vitamin B6 in a dose of 100 mg daily may improve PMS, and improve IQ in children with developmental disorders. SAM-e, also a methyl donor, can help depression in a dose of 400- 1600 mg daily.
- Omega 3 fatty acids, especially DHA, are beneficial for depression, bipolar disorder, as well as schizophrenia and other psychotic disorders. Read the rest of this entry »
Tags: Alternative, Anxiety, Depression, Natural Posted in Mental Health, Nutrition | Comments Off
January 22nd, 2012
Drug companies expediently and glibly list drug actions, meaning beneficial effects for which they are prescribed, separately from another section called side effects, meaning undesirable effects for which they are not prescribed. The action of a statin drug would be the lowering of bad cholesterol to reduce heart attacks and strokes. The side effects would be muscle pain and weakness, liver inflammation, malaise and memory difficulties. It is implied that side effects are unexpected and infrequent, and somehow accidental.
However, the changes resulting from taking a drug are all EFFECTS. Some are good effects and some are bad effects, but they are still EFFECTS. They are predictable from the interference the drug imposes on normal body functions. They are usually dose-related, and do not occur in all people because different bodies have different sensitivities and different rates of metabolism. However, they are not accidental. They are a part of the basic nature of the drug, as an explosion is part of the basic nature of a bomb, and one would have to expect that once in a while an innocent bystander will be blown up.
Read the rest of this entry »
Tags: Medicine, Prescritpion Drugs, Side Effects Posted in Drug Reduction | Comments Off
January 7th, 2012
1. Doctors spending more time with patients
The average office visit for established patients in most practices runs 7-15 minutes, and 30 minutes for new patients. That is barely enough time to get right down to business, do a cursory exam and write a prescription, with no opportunity to learn about the patient’s lifestyle, family difficulties and other stresses. Physicians may be scheduled to see 30-40 patients a day. Being in such a rush stresses the doctor, leads to wrong diagnoses and wrong therapies. It also leads to more drug prescribing and more tests, as the quickest way to dispose of a patient is to write a prescription or order a test. Discussion invariably suffers from neglect.
Our regular office visits last 30 minutes, and new patients receive one hour. Sometimes it is during the last five minutes that patients come out with what is really troubling them. Certainly we arrange enough time to make patients comfortable, to find out about them and their families, and to create a relationship. It is this relationship that fosters healing, an opportunity for the doctor to assert an intention to improve the patient’s well-being.
Electronic medical records have further aggravated the situation, as physicians sit in front of their computers, typing away, scarcely looking at the person in front of them.
The issues we deal with are often sensitive, difficult for patients to express. They deserve, at least, the doctor’s full attention, with eyes on the patient and not on the clock.
2. Better research on nutritional therapies
The quality of nutritional research leaves a lot to be desired. The conclusion reached is often that a nutrient has no effect on a particular outcome. Doses employed in the studies are often low, lower than we employ in our practice, and frequently not obtained from the same source for all patients. The source of the vitamin should be constant, the dose should be substantial, and blood levels should be measured.
Regarding vitamin C, it has been demonstrated that the anti-cancer effect requires a high dose, only achieved through intravenous administration. Also, the effect of folic acid in preventing fetal malformations increases as the dose is raised.
With conventional drug studies, it is established that 80 mg of Lipitor is far more effective than 20 mg in preventing cardiac events. This approach, of using higher doses and comparing them with lower doses, should be employed in nutrient research. There is the further benefit that nutrients are generally safe in high doses.
3. Teach medical students complementary medicine
Medical students and residents often come to our office as part of an elective rotation in complementary medicine. They have had very little if any exposure to nutritional therapies, acupuncture, prolotherapy, or the philosophy of treating medical conditions without drugs or surgery. They should have this instruction as part of their standard medical school curriculum. It should not only be available as an elective, but required as anatomy and biochemistry are required.
Medical education continues to be guided by a drug and surgery paradigm, largely supported by contributions from pharmaceutical companies.
4. Establish safe and sane vaccination protocols for children
Childhood vaccinations are often promoted as completely safe, without side effects, and essential. Pediatricians have dismissed children from their practice when parents refused vaccination for their kids. The list of childhood vaccinations grows without end, and 35 vaccine administrations are now recommended.
In my opinion, a child does not need to be vaccinated against hepatitis B on the first day of life, or be given 5 different vaccines on the same day. A child should be given only one vaccination at a time, and only when he is well. The question of vaccines causing autism remains controversial. Despite research showing no connection between vaccination and autism, many parents trace the onset of autism to vaccination, the MMR vaccine being most suspect. If parents are concerned, they may withhold MMR vaccination until the child is 3 or 4 years old, after which the risk of autism is much reduced.
5. Sponsor education for health, and help people put programs in place
Whatever we are offering now, it is not enough. Causative factors of many chronic diseases are well-known, but correction remains to be implemented. It takes effort to create a healthy life-style, but when people are educated to know how to do so, they are much more likely to try.
Cigarette smoking has declined from 40% of adults to 20% in this country, as a result of education about the ravages of tobacco. We need the same progress in overweight and obesity, which now affect 2/3 of adults, and contribute to heart disease and cancer.
Health expenditures go toward treatment, very little toward prevention. We now have a $3 trillion dollar-a-year medical apparatus, with limited quality of life results.
Strong local, state and federal programs will eventually pay for themselves, as expensive diseases are eliminated.
6. Insurance companies including Medicare should pay for nutritional supplements as they do for drugs.
In our practice we are often able to replace drugs with supplements, providing equal benefits without side effects. Many medications are scarcely more effective than placebo, yet are very expensive. Adverse side effects of medications lead to prescribing of more medications, leading to even more complications. Insurance companies should be required to reimburse for medically prescribed supplements. Several programs already offer this benefit.
7. Awareness that medication may provide relief, but lifestyle provides cure.
A prime example is cardiovascular disease- heart attacks, heart failure and stroke. Approved protocols mandate that patients with heart disease receive beta blockers, ACE inhibitors or ARBs (angiotensin receptor blockers), statins, and aspirin. Physicians are sometimes penalized for not prescribing them. Yet they have not kept cardiovascular disease from being the main cause of death.
Research has been available for over 40 years, from Pritikin, Ornish, and most recently Esselstyn, that a vegan diet, preferably combined with exercise and stress reduction, will prevent and reverse heart disease. We should move in the direction of spreading this information and implementing it. Otherwise we will continue to implement cardiac catheterizations, bypass surgery and stents, costing $100 billion a year.
8. Eliminate addicting drugs
A prime focus of our practice is helping people get off recreational and street drugs, and also prescribed sedatives and psychiatric and sedative medications. Drugs relieve pain, both physical and emotional, but we have come to depend excessively on drugs, with consequent addictions. The most rapid growth of addicting drugs now involves medically prescribed narcotics, affecting 4 million people. I.D. cards for medical marijuana are easily available, though state and federal departments seem unable to agree on whether they are legal. The DEA closes down marijuana shops, only to have them reopen in other locations.
The current paradigm is that if it is prescribed by a physician, it is okay to take. Narcotics are just as addicting whether prescribed or not, and so is marijuana.
9. Reduce psychiatric drugs
Psychiatric drugs are addicting in their own way. They often cause changes in perception, awareness and reality, with considerable disturbance in the patient’s status quo when they are stopped. Many physicians support the use of these medications, without acknowledging that there is a trade-off involved, with side effects of lethargy, reduced libido and impotence, weight gain, loss of concentration, loss of pleasure. The majority of patients prescribed psychiatric drugs stop taking them.
The current paradigm is that the fastest and easiest solution is the best. My experience has been that that is not usually correct. Emotional disturbances can be improved through dietary changes, specific nutritional supplementation, improved sleep, detoxification, changing behavior and relationships, and certain cognitive approaches. Drugs do not solve life problems. They cover them.
Allan Sosin MD
Tags: Doctors, Drugs, Health Insurance, New Year, Research, Supplements Posted in General, IPM News | Comments Off
January 5th, 2012
A woman had suffered from severe sinus symptoms over the course of a year. She had nasal congestion, left maxillary sinus pains, a very hoarse voice that sometimes gave out on her, and a continuous thick greenish nasal discharge. She had been treated with antihistamines and decongestants, multiple courses of antibiotics, local steroids, and finally with sinus surgery when symptoms were unrelenting. The surgery improved her symptoms for about one month, after which they resumed in full.
She was advised to have another, more extensive operation, but figured it was unlikely to work. At our office she was told to eliminate certain foods, especially dairy products, and began treatment with a saline and xylitol nasal spray to cleanse the nasal passages and remove bacteria, irritants and allergens. Another nasal spray contained an antifungal agent, since fungus is often found at the core of sinus conditions, along with an antibiotic and low dose steroid. She received intravenous infusions of high dose vitamin C to suppress inflammation along with other vitamins and minerals including magnesium. She started acupuncture twice a week, which often helps to clear sinus and lung conditions. Allergy desensitization injections against grasses were begun, twice a week.
She installed a strong air filter in her home. Read the rest of this entry »
Tags: Allergies, Sinus Infection Posted in Allergies, Nasal/Respiratory | Comments Off
December 18th, 2011
Diabetic men with low testosterone levels had a death rate twice as high as diabetics with normal testosterone levels, followed over 6 years (20% versus 9%). When men with low testosterone were treated to restore normal levels, the risk of death was the same as men with normal testosterone levels. The study was published in Endocrine Abstracts (2011; 25:P163)
Most of the deaths were due to cardiovascular disease. Average age was 61 years. Testosterone therapy was regulated to restore the men to normal levels, and not higher.
Another study revealed transdermal testosterone replacement provided improvements in insulin resistance, total and LDL cholesterol, and sexual health.
Congestive heart failure is the major cause of hospitalization in people over the age of 65, causing one fifth of hospitalizations, or 875,000 admissions. Half of these patients die within five years.
Testing for testosterone deficiency should be performed in all men with heart failure. Low levels, below 320 ng/ml, should be treated with hormonal support, in the absence of active prostate cancer.
Allan Sosin MD
Tags: Congestive Heart Failure, Men's Health, testosterone Posted in Hormones | Comments Off
December 13th, 2011
Massive research has been undertaken to identify biological causes of mental illness. Business enterprises exist purporting to measure neurotransmitter substances with the intent of guiding drug or nutritional therapies to alter the body’s neurochemical production. I have long been dubious about this testing, seeing no predictable benefit. A similar opinion was offered in JAMA, June 22-29, 2011, page 2580:
“…there is precious little evidence that serotonin, the depressogenic substance in fashion, has anything to do with depression either.”
Walter A. Brown, MD, Dept of psychiatry, Warren Albert Medical School of Brown University, Rhode Island
Allan Sosin, MD
Tags: Depression, Psychiatric Drugs, Serotonin Posted in Mental Health | Comments Off
December 11th, 2011
Berberine is a plant-derived product effective in lowering blood sugar in diabetics, and also in lowering cholesterol levels. The method of action is to increase expression of the insulin receptor. In one study, berberine hydrochloride given to 50 type 2 diabetics lowered HgbA1c by 18%, fasting blood glucose by 25%, and triglycerides by 17%. These effects were similar to those of metformin and of rosiglitazone, two drugs commonly used to treat diabetes.
Our Berberine formulation, called BerberMAX, also contains grapeseed extract. The dosage is 1000 mg, or three capsules daily, in divided doses. We prescribe it alone, mainly for patients with prediabetes, or HgbA1c 5.7-6.5%. It may also be used in combination with Diaxinol, another formulation containing chromium, vanadium and alpha lipoic acid. These supplements act together to further reduce blood sugar.
Berberine is compatible with medications used for treating diabetes. Side effects are minimal. After starting berberine, wait 6-8 weeks before measuring HgbA1C and cholesterol. It takes that long to assess full effects.
Allan Sosin MD
Tags: Berberine, Cholesterol, Insulin Posted in Cardiovascular, Diabetes | Comments Off
December 6th, 2011
The incidence of gout, a painful affliction of the joints, has increased in both men and women in the last 40 years. This coincides with the increased consumption of fructose in foods such as soft drinks and fruit juices. Fructose is known to increase the production of uric acid, the protein breakdown product responsible for gout.
In a study of female nurses (JAMA. 2010;304:2270-8), those who drank two or more servings of soda or fruit juice daily had more than twice the incidence of gout, compared with those who had less than one serving.
As a further warning, gout is strongly associated with a higher incidence of high blood pressure, diabetes, heart disease and kidney disease. Another reason to beware of drinks heavily laden with sugar.
Tags: Fructose, Fruit, Gout, Juice, Soda, Sugar Posted in Chronic Disease | Comments Off
November 29th, 2011
Many patients, most of them women, have symptoms suggestive of underactive thyroid glands, but thyroid blood tests are normal. They complain of constipation, hair loss, cold intolerance, low body temperature, weight gain, fatigue, depression, dry skin, and changes in menstruation. Unless blood tests are abnormal, many physicians decline to offer thyroid hormone therapy.
I have seen a number of patients whose symptoms markedly improved with thyroid hormone supplementation, even though thyroid blood tests were normal. The risk of providing low dose thyroid hormone, starting at 15 mg daily, is quite small, and we have seen no adverse effects at this dose. Symptoms, however, may improve remarkably.
The thyroid gland is sensitive to toxins, and in particular to gluten. Dietary restriction and detoxification have been shown to improve thyroid function. An initial trial of thyroid hormone may offer relief of symptoms while waiting for other changes to be made.
I also suggest a trial of detoxification for anyone with low thyroid. This involves taking nutrients to enhance hepatic detoxification and the release of toxins from fat cells where they are stored, combined with sauna therapy at 140-180 degrees. The program is followed daily for several weeks.
Studies were performed in firefighters and rescue workers engaged in the New York City 9/11 cleanup. Many of them had low thyroid function, which returned to normal after sauna and exercise detoxification.
Allan Sosin MD
Tags: Detoxification, Gluten, Thyroid Posted in Hormones | Comments Off
November 24th, 2011
Along with their many other benefits, omega three fatty acids, primarily found in fish, have now been found protective against the development of heart failure. (Annals of Internal Medicine, 2 August, 2011, pp. 160-170) In adults aged 65 years or older, the incidence of new onset heart failure was substantially lower in subjects with the highest blood concentrations of omega 3 fatty acids. Over an observation period of 10 years, people in the lowest quartile of fish oil concentrations had twice the risk of developing heart failure as those in the highest quartile.
Heart failure is the most common reason for hospitalizations in older adults, and one of the most common causes of death.
This beneficial effect of fish oil likely results from several factors:
- Lower blood pressure
- Increased heart muscle elasticity leading to improved filling during the relaxation phase
- Dilatation of larger blood vessels, with lowering of vascular resistance
- Increased production of nitric oxide to dilate blood vessels
- Increase of HDL (good) cholesterol and lowering of triglycerides
Read the rest of this entry »
Tags: Fish Oil, Heart Disease Posted in Cardiovascular | No Comments »
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