With 3,480 pages of fine print, the Physicians’ Desk Reference (a.k.a. PDR) is not a quick read. That’s because it contains every iota of information on more than 4,000 prescription medications. Heck, the PDR is medication — a humongous sleeping pill.

Doctors count on this compendium to help them make smart prescribing decisions — in other words, to choose drugs that will solve their patients’ medical problems without creating new ones. Unfortunately, it seems some doctors rarely pull the PDR off the shelf. Or if they do crack it open, they don’t stay versed on emerging research that may suddenly make a once-trusted treatment one to avoid. Worst case: You swallow something that has no business being inside your body.

Of course, plenty of M.D.’s do know which prescription and over-the-counter drugs are duds, dangers, or both. So we asked them, “Which medications would you skip?” Their list is your second opinion. If you’re on any of these meds, talk to your doctor. Maybe he or she will finally open that big red book with all the dust on it.

Read the rest of this story at MSNBC News.

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